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RACIAL DIFFERENCES IN ELEVATED C-REACTIVE PROTEIN AMONG U.S. OLDER ADULTS

C-reactive protein (CRP) is a marker of inflammation linked to numerous acute and chronic conditions. Studies have not considered racial differences in elevated CRP among older adults at the national level. We investigate racial differences in elevated CRP and the socioeconomic, psychosocial, behavi...

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Autores principales: Farmer, Heather R, Wray, Linda A, Xu, Hanzhang, Xian, Ying, Pagidipati, Neha, Peterson, Eric D, Dupre, Matthew E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845172/
http://dx.doi.org/10.1093/geroni/igz038.3018
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author Farmer, Heather R
Farmer, Heather R
Wray, Linda A
Xu, Hanzhang
Xian, Ying
Pagidipati, Neha
Peterson, Eric D
Dupre, Matthew E
author_facet Farmer, Heather R
Farmer, Heather R
Wray, Linda A
Xu, Hanzhang
Xian, Ying
Pagidipati, Neha
Peterson, Eric D
Dupre, Matthew E
author_sort Farmer, Heather R
collection PubMed
description C-reactive protein (CRP) is a marker of inflammation linked to numerous acute and chronic conditions. Studies have not considered racial differences in elevated CRP among older adults at the national level. We investigate racial differences in elevated CRP and the socioeconomic, psychosocial, behavioral, and physiological factors that contribute to these differences overall and by gender using a nationally-representative prospective cohort of 14,700 non-Hispanic black and white participants in the Health and Retirement Study followed from 2006 to 2014. Random effects logistic regression models showed that blacks were more likely to have elevated levels of CRP than whites. In men, the racial differences in elevated CRP were attributed to a combination of socioeconomic, psychosocial, and behavioral factors. In women, the racial differences in elevated CRP were primarily attributable to physiological factors. The findings from this work have potentially important implications for clinical practice and interventions targeting vulnerable segments of the population.
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spelling pubmed-68451722019-11-18 RACIAL DIFFERENCES IN ELEVATED C-REACTIVE PROTEIN AMONG U.S. OLDER ADULTS Farmer, Heather R Farmer, Heather R Wray, Linda A Xu, Hanzhang Xian, Ying Pagidipati, Neha Peterson, Eric D Dupre, Matthew E Innov Aging Session 4120 (Symposium) C-reactive protein (CRP) is a marker of inflammation linked to numerous acute and chronic conditions. Studies have not considered racial differences in elevated CRP among older adults at the national level. We investigate racial differences in elevated CRP and the socioeconomic, psychosocial, behavioral, and physiological factors that contribute to these differences overall and by gender using a nationally-representative prospective cohort of 14,700 non-Hispanic black and white participants in the Health and Retirement Study followed from 2006 to 2014. Random effects logistic regression models showed that blacks were more likely to have elevated levels of CRP than whites. In men, the racial differences in elevated CRP were attributed to a combination of socioeconomic, psychosocial, and behavioral factors. In women, the racial differences in elevated CRP were primarily attributable to physiological factors. The findings from this work have potentially important implications for clinical practice and interventions targeting vulnerable segments of the population. Oxford University Press 2019-11-08 /pmc/articles/PMC6845172/ http://dx.doi.org/10.1093/geroni/igz038.3018 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of The Gerontological Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Session 4120 (Symposium)
Farmer, Heather R
Farmer, Heather R
Wray, Linda A
Xu, Hanzhang
Xian, Ying
Pagidipati, Neha
Peterson, Eric D
Dupre, Matthew E
RACIAL DIFFERENCES IN ELEVATED C-REACTIVE PROTEIN AMONG U.S. OLDER ADULTS
title RACIAL DIFFERENCES IN ELEVATED C-REACTIVE PROTEIN AMONG U.S. OLDER ADULTS
title_full RACIAL DIFFERENCES IN ELEVATED C-REACTIVE PROTEIN AMONG U.S. OLDER ADULTS
title_fullStr RACIAL DIFFERENCES IN ELEVATED C-REACTIVE PROTEIN AMONG U.S. OLDER ADULTS
title_full_unstemmed RACIAL DIFFERENCES IN ELEVATED C-REACTIVE PROTEIN AMONG U.S. OLDER ADULTS
title_short RACIAL DIFFERENCES IN ELEVATED C-REACTIVE PROTEIN AMONG U.S. OLDER ADULTS
title_sort racial differences in elevated c-reactive protein among u.s. older adults
topic Session 4120 (Symposium)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845172/
http://dx.doi.org/10.1093/geroni/igz038.3018
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