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Screening identifies small molecules that enhance the maturation of human pluripotent stem cell-derived myotubes

Targeted differentiation of pluripotent stem (PS) cells into myotubes enables in vitro disease modeling of skeletal muscle diseases. Although various protocols achieve myogenic differentiation in vitro, resulting myotubes typically display an embryonic identity. This is a major hurdle for accurately...

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Detalles Bibliográficos
Autores principales:	Selvaraj, Sridhar, Mondragon-Gonzalez, Ricardo, Xu, Bin, Magli, Alessandro, Kim, Hyunkee, Lainé, Jeanne, Kiley, James, Mckee, Holly, Rinaldi, Fabrizio, Aho, Joy, Tabti, Nacira, Shen, Wei, Perlingeiro, Rita CR
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845233/ https://www.ncbi.nlm.nih.gov/pubmed/31710288 http://dx.doi.org/10.7554/eLife.47970

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