PICOLINIC ACID, A TRYPTOPHAN METABOLITE, DOESN’T AFFECT BONE MINERAL DENSITY BUT UPREGULATES LIPID STORAGE GENES

Tryptophan is an essential amino-acid broken down initially to kynurenine (kyn), an immunomodulatory metabolite that we have previously shown to promote bone loss. Kyn levels increase with aging and have also been associated with neurodegenerative disorders. Additional tryptophan metabolites include...

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Detalles Bibliográficos
Autores principales: Isales, Carlos, McGee-Lawrence, Meghan, Hamrick, Mark, Hill, William D, Bollag, Wendy, Ding, Ke-Hong, Shi, Xing-ming, Kennedy, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Session 830 (Poster)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845321/
http://dx.doi.org/10.1093/geroni/igz038.375

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