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PP4 phosphatase cooperates in recombinational DNA repair by enhancing double-strand break end resection

The role of Rad53 in response to a DNA lesion is central for the accurate orchestration of the DNA damage response. Rad53 activation relies on its phosphorylation by Mec1 and its own autophosphorylation in a manner dependent on the adaptor Rad9. While the mechanism behind Rad53 activation has been w...

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Detalles Bibliográficos
Autores principales:	Villoria, María Teresa, Gutiérrez-Escribano, Pilar, Alonso-Rodríguez, Esmeralda, Ramos, Facundo, Merino, Eva, Campos, Adrián, Montoya, Alex, Kramer, Holger, Aragón, Luis, Clemente-Blanco, Andrés
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846210/ https://www.ncbi.nlm.nih.gov/pubmed/31544936 http://dx.doi.org/10.1093/nar/gkz794

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