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CLONAL HEMATOPOIESIS IN A CENTENARIAN COHORT

Mosaicism, the presence of two or more genotypically or karyotypically distinct populations of cells in a single individual, plays an important role in human disease. Mosaicism can result in mutations and/or chromosomal alterations such as loss, gain, or copy-number neutral loss of heterozygosity. C...

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Detalles Bibliográficos
Autores principales: Bhutkar, Aparna, Gurinovich, Anastasia, Perls, Thomas T, Sebastiani, Paola, Monti, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846495/
http://dx.doi.org/10.1093/geroni/igz038.394