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CLONAL HEMATOPOIESIS IN A CENTENARIAN COHORT
Mosaicism, the presence of two or more genotypically or karyotypically distinct populations of cells in a single individual, plays an important role in human disease. Mosaicism can result in mutations and/or chromosomal alterations such as loss, gain, or copy-number neutral loss of heterozygosity. C...
Autores principales: | Bhutkar, Aparna, Gurinovich, Anastasia, Perls, Thomas T, Sebastiani, Paola, Monti, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846495/ http://dx.doi.org/10.1093/geroni/igz038.394 |
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