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ANALYTICAL CONSIDERATIONS OF DEVELOPING A PHENOTYPIC AGING MEASURE: THE CONCEPTUAL FRAMEWORK MUST COME FIRST!

We propose a latent structural model framework where phenotypic aging is a latent variable influenced by chronological age, genes and environment. Within this framework, phenotypic age influences aging-related outcomes and is reflected by latent domains of aging (body composition, energetics, homeos...

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Detalles Bibliográficos
Autores principales: Shardell, Michelle, Kuo, Pei-Lun, Schrack, Jennifer, Simonsick, Eleanor M, Resnick, Susan M, Levine, Morgan E, Ferrucci, luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846545/
http://dx.doi.org/10.1093/geroni/igz038.2148