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THE ROLE OF CAPRIN-1 PROTEIN DYSREGULATION IN SYNAPSE DECLINE LEADING TO PROGRESSION OF TAUOPATHIES
Many neurodegenerative diseases are characterized by accumulation of proteins such as tau, a microtubule stabilization protein. Toxic tau forms tangles and affects neuronal synapse function, an early step of neurodegeneration. To focus on synapse function, we highlighted Caprin-1 protein. Through ge...
Autores principales: | Fastenau, Caitlyn, Cifuentes, Helen, Kauwe, Grant, Tracy, Tara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846662/ http://dx.doi.org/10.1093/geroni/igz038.3078 |
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