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4-PHENYLBUTYRATE: MOLECULAR MECHANISMS AND AGING INTERVENTION POTENTIAL

4-Phenylbutyrate (PBA) is a FDA approved drug for treating patients with urea cycle disorders. Additionally, PBA acts upon several pathways thought of as important modifiers of aging including: histone deacetylation, proteostasis as a chemical chaperone, and stress resistance by regulating expressio...

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Detalles Bibliográficos
Autores principales:	Bene, Michael R, Thyne, Kevin, Dorigatti, Jonathan, Salmon, Adam B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Session 830 (Poster)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846695/ http://dx.doi.org/10.1093/geroni/igz038.379

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