Cargando…
CARDIOVASCULAR HEALTH AND SUCCESSFUL AGING: THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS
Individual risk factors have been shown to be associated with successful aging. However, the combined effect of behaviors and biomarkers on successful aging remains unclear. By using the Multi-Ethnic Study of Atherosclerosis (MESA) dataset, this study was to examine the association of AHA’s Cardiova...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846711/ http://dx.doi.org/10.1093/geroni/igz038.2394 |
_version_ | 1783468938475077632 |
---|---|
author | Lan, Tzuo-Yun Krefman, Amy Bancks, Michael Shea, Steven Liu, Kiang Allen, Norrina |
author_facet | Lan, Tzuo-Yun Krefman, Amy Bancks, Michael Shea, Steven Liu, Kiang Allen, Norrina |
author_sort | Lan, Tzuo-Yun |
collection | PubMed |
description | Individual risk factors have been shown to be associated with successful aging. However, the combined effect of behaviors and biomarkers on successful aging remains unclear. By using the Multi-Ethnic Study of Atherosclerosis (MESA) dataset, this study was to examine the association of AHA’s Cardiovascular Health (CVH) with successful aging. A total of 1,597 who were followed from baseline (2000-2002) at age 49-64 through exam 6 (2016-2018) at age 65-80 were included. CVH, including smoking, body mass index (BMI), physical activity, diet, blood pressure, cholesterol, and blood glucose, was measured at baseline. The CVH score, ranging from 0-14, was divided into ideal (11–14), intermediate (9–10), and poor (0–8) groups. Normal or successful aging, defined as avoiding major disease (including cancer, cardiovascular, or severe lung or kidney diseases), no disability, high cognitive function, high physical functioning, and engagement with life, was assessed at exam 6. We compared the cumulative incidence of successful aging among three groups. Modified Poisson regression model was employed to estimate relative risk (RR) adjusting for age, gender, race, education, income, marital status, and alcohol consumption. Among study participants at baseline, 36% were in ideal, 39% in Intermediate, and 25% in poor CVH. By exam 6, only 18% met the criteria for successful aging. Compared with the poor group, the adjusted RRs (95 % CI) of successful aging for the intermediate and ideal groups were 1.78 (1.23-2.56) and 2.56 (1.79-3.67). Our data suggest that CVH in midlife is associated with successful aging in later life. |
format | Online Article Text |
id | pubmed-6846711 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-68467112019-11-18 CARDIOVASCULAR HEALTH AND SUCCESSFUL AGING: THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS Lan, Tzuo-Yun Krefman, Amy Bancks, Michael Shea, Steven Liu, Kiang Allen, Norrina Innov Aging Session 3280 (Poster) Individual risk factors have been shown to be associated with successful aging. However, the combined effect of behaviors and biomarkers on successful aging remains unclear. By using the Multi-Ethnic Study of Atherosclerosis (MESA) dataset, this study was to examine the association of AHA’s Cardiovascular Health (CVH) with successful aging. A total of 1,597 who were followed from baseline (2000-2002) at age 49-64 through exam 6 (2016-2018) at age 65-80 were included. CVH, including smoking, body mass index (BMI), physical activity, diet, blood pressure, cholesterol, and blood glucose, was measured at baseline. The CVH score, ranging from 0-14, was divided into ideal (11–14), intermediate (9–10), and poor (0–8) groups. Normal or successful aging, defined as avoiding major disease (including cancer, cardiovascular, or severe lung or kidney diseases), no disability, high cognitive function, high physical functioning, and engagement with life, was assessed at exam 6. We compared the cumulative incidence of successful aging among three groups. Modified Poisson regression model was employed to estimate relative risk (RR) adjusting for age, gender, race, education, income, marital status, and alcohol consumption. Among study participants at baseline, 36% were in ideal, 39% in Intermediate, and 25% in poor CVH. By exam 6, only 18% met the criteria for successful aging. Compared with the poor group, the adjusted RRs (95 % CI) of successful aging for the intermediate and ideal groups were 1.78 (1.23-2.56) and 2.56 (1.79-3.67). Our data suggest that CVH in midlife is associated with successful aging in later life. Oxford University Press 2019-11-08 /pmc/articles/PMC6846711/ http://dx.doi.org/10.1093/geroni/igz038.2394 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of The Gerontological Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Session 3280 (Poster) Lan, Tzuo-Yun Krefman, Amy Bancks, Michael Shea, Steven Liu, Kiang Allen, Norrina CARDIOVASCULAR HEALTH AND SUCCESSFUL AGING: THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS |
title | CARDIOVASCULAR HEALTH AND SUCCESSFUL AGING: THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS |
title_full | CARDIOVASCULAR HEALTH AND SUCCESSFUL AGING: THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS |
title_fullStr | CARDIOVASCULAR HEALTH AND SUCCESSFUL AGING: THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS |
title_full_unstemmed | CARDIOVASCULAR HEALTH AND SUCCESSFUL AGING: THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS |
title_short | CARDIOVASCULAR HEALTH AND SUCCESSFUL AGING: THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS |
title_sort | cardiovascular health and successful aging: the multi-ethnic study of atherosclerosis |
topic | Session 3280 (Poster) |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846711/ http://dx.doi.org/10.1093/geroni/igz038.2394 |
work_keys_str_mv | AT lantzuoyun cardiovascularhealthandsuccessfulagingthemultiethnicstudyofatherosclerosis AT krefmanamy cardiovascularhealthandsuccessfulagingthemultiethnicstudyofatherosclerosis AT bancksmichael cardiovascularhealthandsuccessfulagingthemultiethnicstudyofatherosclerosis AT sheasteven cardiovascularhealthandsuccessfulagingthemultiethnicstudyofatherosclerosis AT liukiang cardiovascularhealthandsuccessfulagingthemultiethnicstudyofatherosclerosis AT allennorrina cardiovascularhealthandsuccessfulagingthemultiethnicstudyofatherosclerosis |