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EFFECT OF CALORIC RESTRICTION AND RAPAMYCIN ON OVARIAN AGING IN MICE
The ovarian follicular reserve of primordial follicle declines with aging in female mammals. Caloric restriction (CR) has been shown to increase the preservation of the ovarian follicular reserve. Likewise, rapamycin has similar effects to CR on the ovarian reserve. Therefore, the aim of our study w...
Autores principales: | Garcia, Driele, Saccon, Tatiana, Rincon, Joao, Pradiee, Jorgea, Mondadori, Rafael, Masternak, Michal, Bartke, Andrzej, Schneider, Augusto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846715/ http://dx.doi.org/10.1093/geroni/igz038.385 |
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