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Synonymous genome recoding: a tool to explore microbial biology and new therapeutic strategies
Synthetic genome recoding is a new means of generating designed organisms with altered phenotypes. Synonymous mutations introduced into the protein coding region tolerate modifications in DNA or mRNA without modifying the encoded proteins. Synonymous genome-wide recoding has allowed the synthetic ge...
Autores principales: | Martínez, Miguel Angel, Jordan-Paiz, Ana, Franco, Sandra, Nevot, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846928/ https://www.ncbi.nlm.nih.gov/pubmed/31584076 http://dx.doi.org/10.1093/nar/gkz831 |
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