Structural insights into synthetic ligands targeting A–A pairs in disease-related CAG RNA repeats

The trinucleotide repeat expansion disorders (TREDs) constitute of a group of >40 hereditary neurodegenerative human diseases associated with abnormal expansion of repeated sequences, such as CAG repeats. The pathogenic factor is a transcribed RNA or protein whose function in the cell is compromi...

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Detalles Bibliográficos
Autores principales: Mukherjee, Sanjukta, Błaszczyk, Leszek, Rypniewski, Wojciech, Falschlunger, Christoph, Micura, Ronald, Murata, Asako, Dohno, Chikara, Nakatani, Kazuhiko, Kiliszek, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847237/
https://www.ncbi.nlm.nih.gov/pubmed/31566242
http://dx.doi.org/10.1093/nar/gkz832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847237/
https://www.ncbi.nlm.nih.gov/pubmed/31566242
http://dx.doi.org/10.1093/nar/gkz832

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