Sunitinib cause delayed complete response on metastatic RCC and extensive IVC thrombus, but not to the kidney tumor: a case report and review of literature

The role of cytoreductive nephrectomy for metastatic renal cell carcinoma (RCC) is currently debated, with the advancements in target therapy development. The aim of our work was to present an interesting case report with mini review to describe the important role of cytoreductive nephrectomy for ki...

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Autores principales: Beltagy, Ahmad, Ismail, Asmaa, Elmansy, Hazem, Shahrour, Walid, Prowse, Owen, Kotb, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847936/
https://www.ncbi.nlm.nih.gov/pubmed/31737248
http://dx.doi.org/10.1093/jscr/rjz326
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author Beltagy, Ahmad
Ismail, Asmaa
Elmansy, Hazem
Shahrour, Walid
Prowse, Owen
Kotb, Ahmed
author_facet Beltagy, Ahmad
Ismail, Asmaa
Elmansy, Hazem
Shahrour, Walid
Prowse, Owen
Kotb, Ahmed
author_sort Beltagy, Ahmad
collection PubMed
description The role of cytoreductive nephrectomy for metastatic renal cell carcinoma (RCC) is currently debated, with the advancements in target therapy development. The aim of our work was to present an interesting case report with mini review to describe the important role of cytoreductive nephrectomy for kidney cancer control that failed to respond well to Sutent, in spite of good response for all metastases. Medline review of related English publication was conducted and included to the study. RCC response to Sutent is inferior to the response of its metastases. Cytoreductive nephrectomy still plays an important role in metastatic RCC and may be an integral part for cancer control, in properly selected patients.
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spelling pubmed-68479362019-11-15 Sunitinib cause delayed complete response on metastatic RCC and extensive IVC thrombus, but not to the kidney tumor: a case report and review of literature Beltagy, Ahmad Ismail, Asmaa Elmansy, Hazem Shahrour, Walid Prowse, Owen Kotb, Ahmed J Surg Case Rep Case Report The role of cytoreductive nephrectomy for metastatic renal cell carcinoma (RCC) is currently debated, with the advancements in target therapy development. The aim of our work was to present an interesting case report with mini review to describe the important role of cytoreductive nephrectomy for kidney cancer control that failed to respond well to Sutent, in spite of good response for all metastases. Medline review of related English publication was conducted and included to the study. RCC response to Sutent is inferior to the response of its metastases. Cytoreductive nephrectomy still plays an important role in metastatic RCC and may be an integral part for cancer control, in properly selected patients. Oxford University Press 2019-11-11 /pmc/articles/PMC6847936/ /pubmed/31737248 http://dx.doi.org/10.1093/jscr/rjz326 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2019. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Beltagy, Ahmad
Ismail, Asmaa
Elmansy, Hazem
Shahrour, Walid
Prowse, Owen
Kotb, Ahmed
Sunitinib cause delayed complete response on metastatic RCC and extensive IVC thrombus, but not to the kidney tumor: a case report and review of literature
title Sunitinib cause delayed complete response on metastatic RCC and extensive IVC thrombus, but not to the kidney tumor: a case report and review of literature
title_full Sunitinib cause delayed complete response on metastatic RCC and extensive IVC thrombus, but not to the kidney tumor: a case report and review of literature
title_fullStr Sunitinib cause delayed complete response on metastatic RCC and extensive IVC thrombus, but not to the kidney tumor: a case report and review of literature
title_full_unstemmed Sunitinib cause delayed complete response on metastatic RCC and extensive IVC thrombus, but not to the kidney tumor: a case report and review of literature
title_short Sunitinib cause delayed complete response on metastatic RCC and extensive IVC thrombus, but not to the kidney tumor: a case report and review of literature
title_sort sunitinib cause delayed complete response on metastatic rcc and extensive ivc thrombus, but not to the kidney tumor: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847936/
https://www.ncbi.nlm.nih.gov/pubmed/31737248
http://dx.doi.org/10.1093/jscr/rjz326
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