CD137 Co-Stimulation Improves The Antitumor Effect Of LMP1-Specific Chimeric Antigen Receptor T Cells In Vitro And In Vivo

PURPOSE: In previous research, we have found that LMP1-specific chimeric antigen (HELA/CAR) T cells can specifically recognize and kill LMP1-positive NPC cells. However, the tumor-inhibitory effectiveness of HELA/CART cells needs to be enhanced. METHODS: We created two CARs that contain the T cell r...

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Detalles Bibliográficos
Autores principales: Tang, Xiaojun, Tang, Qi, Mao, Yuan, Huang, Xiaochen, Jia, Lizhou, Zhu, Jin, Feng, Zhenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847990/
https://www.ncbi.nlm.nih.gov/pubmed/31807014
http://dx.doi.org/10.2147/OTT.S221040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847990/
https://www.ncbi.nlm.nih.gov/pubmed/31807014
http://dx.doi.org/10.2147/OTT.S221040

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