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ERICH3 in Primary Cilia Regulates Cilium Formation and the Localisations of Ciliary Transport and Sonic Hedgehog Signaling Proteins

Intraflagellar transport (IFT) is essential for the formation and function of the microtubule-based primary cilium, which acts as a sensory and signalling device at the cell surface. Consisting of IFT-A/B and BBSome cargo adaptors that associate with molecular motors, IFT transports protein into (an...

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Detalles Bibliográficos
Autores principales: Alsolami, Mona, Kuhns, Stefanie, Alsulami, Manal, Blacque, Oliver E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848114/
https://www.ncbi.nlm.nih.gov/pubmed/31712586
http://dx.doi.org/10.1038/s41598-019-52830-1