Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish

Two essential key events in acrylamide (ACR) acute neurotoxicity are the formation of adducts with nucleophilic sulfhydryl groups on cysteine residues of selected proteins in the synaptic terminals and the depletion of the glutathione (GSx) stores in neural tissue. The use of N-acetylcysteine (NAC)...

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Detalles Bibliográficos
Autores principales: Faria, Melissa, Prats, Eva, Gómez-Canela, Cristian, Hsu, Chuan-Yu, Arick, Mark A., Bedrossiantz, Juliette, Orozco, Manuel, Garcia-Reyero, Natàlia, Ziv, Tamar, Ben-Lulu, Shani, Admon, Arie, Gómez-Oliván, Leobardo Manuel, Raldúa, Demetrio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848153/
https://www.ncbi.nlm.nih.gov/pubmed/31712630
http://dx.doi.org/10.1038/s41598-019-53154-w

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