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From expression footprints to causal pathways: contextualizing large signaling networks with CARNIVAL

While gene expression profiling is commonly used to gain an overview of cellular processes, the identification of upstream processes that drive expression changes remains a challenge. To address this issue, we introduce CARNIVAL, a causal network contextualization tool which derives network architec...

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Detalles Bibliográficos
Autores principales: Liu, Anika, Trairatphisan, Panuwat, Gjerga, Enio, Didangelos, Athanasios, Barratt, Jonathan, Saez-Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848167/
https://www.ncbi.nlm.nih.gov/pubmed/31728204
http://dx.doi.org/10.1038/s41540-019-0118-z