RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2

Sex determination of the gonads begins with fate specification of gonadal supporting cells into either ovarian pre-granulosa cells or testicular Sertoli cells. This fate specification hinges on a balance of transcriptional control. Here we report that expression of the transcription factor RUNX1 is...

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Detalles Bibliográficos
Autores principales: Nicol, Barbara, Grimm, Sara A., Chalmel, Frédéric, Lecluze, Estelle, Pannetier, Maëlle, Pailhoux, Eric, Dupin-De-Beyssat, Elodie, Guiguen, Yann, Capel, Blanche, Yao, Humphrey H.-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848188/
https://www.ncbi.nlm.nih.gov/pubmed/31712577
http://dx.doi.org/10.1038/s41467-019-13060-1

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