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Oncogenes, tumor suppressor and differentiation genes represent the oldest human gene classes and evolve concurrently
Earlier we showed that human genome contains many evolutionarily young or novel genes with tumor-specific or tumor-predominant expression. We suggest calling such genes Tumor Specifically Expressed, Evolutionarily New (TSEEN) genes. In this paper we performed a study of the evolutionary ages of diff...
Autores principales: | Makashov, A. A., Malov, S. V., Kozlov, A. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848199/ https://www.ncbi.nlm.nih.gov/pubmed/31712655 http://dx.doi.org/10.1038/s41598-019-52835-w |
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