Cargando…

Mild chronic perturbation of inhibition severely alters hippocampal function

Pentameric GABA(A) receptors mediate a large share of CNS inhibition. The γ2 subunit is a typical constituent. At least 11 mutations in the γ2 subunit cause human epilepsies, making the role of γ2-containing receptors in brain function of keen basic and translational interest. How small changes to i...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Min-Yu, Ziolkowski, Luke, Lambert, Peter, Shu, Hong-Jin, Keiser, Micah, Rensing, Nicholas, Warikoo, Natasha, Martinek, Monika, Platnick, Carson, Benz, Ann, Bracamontes, John, Akk, Gustav, Steinbach, Joe Henry, Zorumski, Charles F., Wong, Michael, Mennerick, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848214/
https://www.ncbi.nlm.nih.gov/pubmed/31712706
http://dx.doi.org/10.1038/s41598-019-52851-w

Ejemplares similares