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Mild chronic perturbation of inhibition severely alters hippocampal function
Pentameric GABA(A) receptors mediate a large share of CNS inhibition. The γ2 subunit is a typical constituent. At least 11 mutations in the γ2 subunit cause human epilepsies, making the role of γ2-containing receptors in brain function of keen basic and translational interest. How small changes to i...
Autores principales: | Sun, Min-Yu, Ziolkowski, Luke, Lambert, Peter, Shu, Hong-Jin, Keiser, Micah, Rensing, Nicholas, Warikoo, Natasha, Martinek, Monika, Platnick, Carson, Benz, Ann, Bracamontes, John, Akk, Gustav, Steinbach, Joe Henry, Zorumski, Charles F., Wong, Michael, Mennerick, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848214/ https://www.ncbi.nlm.nih.gov/pubmed/31712706 http://dx.doi.org/10.1038/s41598-019-52851-w |
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