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Telomere Length Maintenance and Its Transcriptional Regulation in Lynch Syndrome and Sporadic Colorectal Carcinoma

Background: Activation of telomere maintenance mechanisms (TMMs) is a hallmark of most cancers, and is required to prevent genome instability and to establish cellular immortality through reconstitution of capping of chromosome ends. TMM depends on the cancer type. Comparative studies linking tumor...

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Detalles Bibliográficos
Autores principales:	Nersisyan, Lilit, Hopp, Lydia, Loeffler-Wirth, Henry, Galle, Jörg, Loeffler, Markus, Arakelyan, Arsen, Binder, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848383/ https://www.ncbi.nlm.nih.gov/pubmed/31750255 http://dx.doi.org/10.3389/fonc.2019.01172

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