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Prediction of Deleterious Non-synonymous SNPs of Human STK11 Gene by Combining Algorithms, Molecular Docking, and Molecular Dynamics Simulation

Serine-threonine kinase11 (STK11) is a tumor suppressor gene which plays a key role in regulating cell growth and apoptosis. It is widely known as a multitasking kinase and engaged in cell polarity, cell cycle arrest, chromatin remodeling, energy metabolism, and Wnt signaling. The substitutions of s...

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Detalles Bibliográficos
Autores principales:	Islam, Md. Jahirul, Khan, Akib Mahmud, Parves, Md. Rimon, Hossain, Md Nayeem, Halim, Mohammad A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848484/ https://www.ncbi.nlm.nih.gov/pubmed/31712642 http://dx.doi.org/10.1038/s41598-019-52308-0

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