Effect of initial pH, different nitrogen sources, and cultivation time on the production of yellow or orange Monascus purpureus pigments and the mycotoxin citrinin

Monascus purpureus was grown in submerged liquid culture using ammonium sulfate, sodium nitrate, and peptone as nitrogen sources while initial medium pH was adjusted to 2.5, 5.5, 6.5, or 8.0. The combined effect of culture pH and nitrogen source on the biosynthesis of yellow (ankaflavin and monascin...

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Autores principales: Patrovsky, Matej, Sinovska, Kristyna, Branska, Barbora, Patakova, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848812/
https://www.ncbi.nlm.nih.gov/pubmed/31763000
http://dx.doi.org/10.1002/fsn3.1197
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author Patrovsky, Matej
Sinovska, Kristyna
Branska, Barbora
Patakova, Petra
author_facet Patrovsky, Matej
Sinovska, Kristyna
Branska, Barbora
Patakova, Petra
author_sort Patrovsky, Matej
collection PubMed
description Monascus purpureus was grown in submerged liquid culture using ammonium sulfate, sodium nitrate, and peptone as nitrogen sources while initial medium pH was adjusted to 2.5, 5.5, 6.5, or 8.0. The combined effect of culture pH and nitrogen source on the biosynthesis of yellow (ankaflavin and monascin) and orange (rubropunctatin and monascorubrin) pigments, plus the mycotoxin citrinin, was evaluated chromatographically. Optimum cultivation conditions, that is, initial pH 2.5 and 8.8 g/L peptone as a nitrogen source, resulted in high levels of production of yellow and orange pigments (sum of pigment concentration 1,138 mg/L) and negligible citrinin concentration (2 mg/L).
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spelling pubmed-68488122019-11-22 Effect of initial pH, different nitrogen sources, and cultivation time on the production of yellow or orange Monascus purpureus pigments and the mycotoxin citrinin Patrovsky, Matej Sinovska, Kristyna Branska, Barbora Patakova, Petra Food Sci Nutr Original Research Monascus purpureus was grown in submerged liquid culture using ammonium sulfate, sodium nitrate, and peptone as nitrogen sources while initial medium pH was adjusted to 2.5, 5.5, 6.5, or 8.0. The combined effect of culture pH and nitrogen source on the biosynthesis of yellow (ankaflavin and monascin) and orange (rubropunctatin and monascorubrin) pigments, plus the mycotoxin citrinin, was evaluated chromatographically. Optimum cultivation conditions, that is, initial pH 2.5 and 8.8 g/L peptone as a nitrogen source, resulted in high levels of production of yellow and orange pigments (sum of pigment concentration 1,138 mg/L) and negligible citrinin concentration (2 mg/L). John Wiley and Sons Inc. 2019-09-27 /pmc/articles/PMC6848812/ /pubmed/31763000 http://dx.doi.org/10.1002/fsn3.1197 Text en © 2019 The Authors. Food Science & Nutrition published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Patrovsky, Matej
Sinovska, Kristyna
Branska, Barbora
Patakova, Petra
Effect of initial pH, different nitrogen sources, and cultivation time on the production of yellow or orange Monascus purpureus pigments and the mycotoxin citrinin
title Effect of initial pH, different nitrogen sources, and cultivation time on the production of yellow or orange Monascus purpureus pigments and the mycotoxin citrinin
title_full Effect of initial pH, different nitrogen sources, and cultivation time on the production of yellow or orange Monascus purpureus pigments and the mycotoxin citrinin
title_fullStr Effect of initial pH, different nitrogen sources, and cultivation time on the production of yellow or orange Monascus purpureus pigments and the mycotoxin citrinin
title_full_unstemmed Effect of initial pH, different nitrogen sources, and cultivation time on the production of yellow or orange Monascus purpureus pigments and the mycotoxin citrinin
title_short Effect of initial pH, different nitrogen sources, and cultivation time on the production of yellow or orange Monascus purpureus pigments and the mycotoxin citrinin
title_sort effect of initial ph, different nitrogen sources, and cultivation time on the production of yellow or orange monascus purpureus pigments and the mycotoxin citrinin
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848812/
https://www.ncbi.nlm.nih.gov/pubmed/31763000
http://dx.doi.org/10.1002/fsn3.1197
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