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Can ELABELA be a novel target in the treatment of chronic lymphocytic leukaemia?

BACKGROUND: It has been shown that bcl2, bcl-XL and mcl-1 protein levels are high in chronic lymphocytic leukemia cells, and resultantly, apoptosis does not occur chronic lymphocytic leukemia cells. Apelin and apela (ELABELA/ELA/Toddler) are two peptide ligands for a class A G-protein coupled recept...

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Detalles Bibliográficos
Autores principales:	Acik, Didar Yanardag, Bankir, Mehmet, Baylan, Filiz Alkan, Aygun, Bilal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849261/ https://www.ncbi.nlm.nih.gov/pubmed/31718601 http://dx.doi.org/10.1186/s12885-019-6325-6

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