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Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model
BACKGROUND: Enterovirus 71 (EV71 or EV-A71) was first identified in California about half a century ago. In recent years, outbreaks of EV-A71 were prevalent worldwide, including Taiwan, Malaysia, Singapore, Japan, and China. Between 2008 and 2011, China alone reported 1894 deaths associated with EV-...
Autores principales: | Liou, An-Ting, Liao, Chun-Che, Chou, Shu-Fan, Chang, Ya-Shu, Chang, Chih-Shin, Shih, Chiaho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849267/ https://www.ncbi.nlm.nih.gov/pubmed/31711481 http://dx.doi.org/10.1186/s12929-019-0585-y |
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