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Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis

BACKGROUND: Notch1 signalling is a stem-cell-related pathway that is essential for embryonic development, tissue regeneration and organogenesis. However, the role of Notch1 in the formation of myofibroblasts and fibrosis in kidneys following injury remains unknown. METHODS: The activity of Notch1 si...

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Detalles Bibliográficos
Autores principales:	Hong, Weilong, Zhang, Ge, Lu, Hong, Guo, Yangyang, Zheng, Shizhang, Zhu, Hengyue, Xiao, Yanyi, Papa, Akuetteh Percy David, Wu, Cunzao, Sun, Linxiao, Chen, Bicheng, Bai, Yongheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849313/ https://www.ncbi.nlm.nih.gov/pubmed/31718671 http://dx.doi.org/10.1186/s12964-019-0455-y

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