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Theranostic Application of a Novel G-Quadruplex-Forming DNA Aptamer Targeting Malate Synthase of Mycobacterium tuberculosis

The successful management of tuberculosis (TB) requires efficient diagnosis and treatment. Further, the increasing prevalence of drug-resistant TB highlights the urgent need to develop novel inhibitors against both drug-susceptible and drug-resistant forms of disease. Malate synthase (MS), an enzyme...

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Detalles Bibliográficos
Autores principales: Dhiman, Abhijeet, Kumar, Chanchal, Mishra, Subodh Kumar, Sikri, Kriti, Datta, Ishara, Sharma, Pradeep, Singh, Tej P., Haldar, Sagarika, Sharma, Neera, Bansal, Anjali, Ahmad, Yusra, Kumar, Amit, Sharma, Tarun Kumar, Tyagi, Jaya Sivaswami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849348/
https://www.ncbi.nlm.nih.gov/pubmed/31704587
http://dx.doi.org/10.1016/j.omtn.2019.09.026