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Mucosal IL13RA2 expression predicts nonresponse to anti‐TNF therapy in Crohn's disease
BACKGROUND: Ileocolonic expression of IL13RA2 has been identified as a predictive marker for nonresponsiveness to infliximab (IFX) in patients with Crohn's disease (CD). AIM: To validate the IL13RA2 biomarker, study its anti‐TNF specificity and get a better understanding of the underlying biolo...
Autores principales: | Verstockt, Bram, Verstockt, Sare, Creyns, Brecht, Tops, Sophie, Van Assche, Gert, Gils, Ann, Ceuppens, Jan L., Vermeire, Séverine, Ferrante, Marc, Breynaert, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849553/ https://www.ncbi.nlm.nih.gov/pubmed/30663072 http://dx.doi.org/10.1111/apt.15126 |
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