Dimethyl fumarate impairs differentiated B cells and fosters central nervous system integrity in treatment of multiple sclerosis

In multiple sclerosis (MS), the effect of dimethyl fumarate (DMF) treatment is primarily attributed to its capacity to dampen pathogenic T cells. Here, we tested whether DMF also modulates B cells, which are newly recognized key players in MS, and to which extent DMF restricts ongoing loss of oligod...

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Detalles Bibliográficos
Autores principales: Traub, Jan, Traffehn, Sarah, Ochs, Jasmin, Häusser‐Kinzel, Silke, Stephan, Schirin, Scannevin, Robert, Brück, Wolfgang, Metz, Imke, Weber, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849574/
https://www.ncbi.nlm.nih.gov/pubmed/30706542
http://dx.doi.org/10.1111/bpa.12711

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