Canonical DNA minor groove insertion of bisbenzamidine–Ru(ii) complexes with chiral selectivity

We report the first Ru(ii) coordination compounds that interact with DNA through a canonical minor groove insertion mode and with selectivity for A/T rich sites. This was made possible by integrating a bis-benzamidine minor groove DNA-binding agent with a ruthenium(ii) complex. Importantly, one of t...

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Detalles Bibliográficos
Autores principales: Sánchez, Mateo I., Rama, Gustavo, Calo-Lapido, Renata, Ucar, Kübra, Lincoln, Per, López, Miguel Vázquez, Melle-Franco, Manuel, Mascareñas, José L., Vázquez, M. Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849638/
https://www.ncbi.nlm.nih.gov/pubmed/31803441
http://dx.doi.org/10.1039/c9sc03053k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849638/
https://www.ncbi.nlm.nih.gov/pubmed/31803441
http://dx.doi.org/10.1039/c9sc03053k

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