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The anti-cancer effects of phenformin in thyroid cancer cell lines and in normal thyrocytes

Phenformin is a biguanide drug which, besides the original anti-diabetic effect, also exerts anti-cancer effects. The aim of this study was to further characterize these latter in terms of both cell-viability and modulation of the secretion of the pro-tumorigenic chemokine CXCL8. Normal human thyroc...

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Detalles Bibliográficos
Autores principales: Coperchini, Francesca, Croce, Laura, Denegri, Marco, Awwad, Oriana, Ngnitejeu, Samuel Tata, Magri, Flavia, Chiovato, Luca, Rotondi, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849649/
https://www.ncbi.nlm.nih.gov/pubmed/31741708
http://dx.doi.org/10.18632/oncotarget.27266