Cargando…

Linear growth faltering and the role of weight attainment: Prospective analysis of young children recovering from severe wasting in Niger

Efforts to reduce the impact of stunting have been largely independent of interventions to reduce the impact of wasting, despite the observation that the conditions can coexist in the same child and increase risk of death. To optimize the management of malnourished children—who can be wasted, stunte...

Descripción completa

Detalles Bibliográficos
Autores principales: Isanaka, Sheila, Hitchings, Matt D.T., Berthé, Fatou, Briend, André, Grais, Rebecca F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849732/
https://www.ncbi.nlm.nih.gov/pubmed/30903806
http://dx.doi.org/10.1111/mcn.12817
_version_ 1783469264177463296
author Isanaka, Sheila
Hitchings, Matt D.T.
Berthé, Fatou
Briend, André
Grais, Rebecca F.
author_facet Isanaka, Sheila
Hitchings, Matt D.T.
Berthé, Fatou
Briend, André
Grais, Rebecca F.
author_sort Isanaka, Sheila
collection PubMed
description Efforts to reduce the impact of stunting have been largely independent of interventions to reduce the impact of wasting, despite the observation that the conditions can coexist in the same child and increase risk of death. To optimize the management of malnourished children—who can be wasted, stunted, or both—the relationship between stunting and wasting should be elaborated. We aimed to describe the relationship between concurrent weight and height gain during and after rehabilitation from severe wasting. We conducted a secondary analysis of a randomized trial for the outpatient treatment of severe wasting, including 1,542 children who recovered and were followed for 12 weeks. We described the overlap of stunting and severe wasting and the change in stunting over time. We showed the relationship between concurrent weight and height gain using adjusted generalized estimating equations and calculated the mean rate of change in weight‐for‐height z score (WHZ) and height‐for‐age z score (HAZ) during and after rehabilitation. At baseline, 79% (n = 1,223/1,542) and 49% (n = 757/1,542) of children were stunted and severely stunted, respectively. Prevalence increased over time among children <24 months. During rehabilitation when weight was not yet fully recovered, we found rapid WHZ gain but limited HAZ gain. Following successful rehabilitation, WHZ gain slowed. The rate of HAZ gain was negative after rehabilitation but increased relative to the period during treatment. The potential relationship between weight and height gain calls for increased coverage of wasting treatment to not only prevent child mortality but also reduce linear growth faltering.
format Online
Article
Text
id pubmed-6849732
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-68497322019-11-15 Linear growth faltering and the role of weight attainment: Prospective analysis of young children recovering from severe wasting in Niger Isanaka, Sheila Hitchings, Matt D.T. Berthé, Fatou Briend, André Grais, Rebecca F. Matern Child Nutr Original Articles Efforts to reduce the impact of stunting have been largely independent of interventions to reduce the impact of wasting, despite the observation that the conditions can coexist in the same child and increase risk of death. To optimize the management of malnourished children—who can be wasted, stunted, or both—the relationship between stunting and wasting should be elaborated. We aimed to describe the relationship between concurrent weight and height gain during and after rehabilitation from severe wasting. We conducted a secondary analysis of a randomized trial for the outpatient treatment of severe wasting, including 1,542 children who recovered and were followed for 12 weeks. We described the overlap of stunting and severe wasting and the change in stunting over time. We showed the relationship between concurrent weight and height gain using adjusted generalized estimating equations and calculated the mean rate of change in weight‐for‐height z score (WHZ) and height‐for‐age z score (HAZ) during and after rehabilitation. At baseline, 79% (n = 1,223/1,542) and 49% (n = 757/1,542) of children were stunted and severely stunted, respectively. Prevalence increased over time among children <24 months. During rehabilitation when weight was not yet fully recovered, we found rapid WHZ gain but limited HAZ gain. Following successful rehabilitation, WHZ gain slowed. The rate of HAZ gain was negative after rehabilitation but increased relative to the period during treatment. The potential relationship between weight and height gain calls for increased coverage of wasting treatment to not only prevent child mortality but also reduce linear growth faltering. John Wiley and Sons Inc. 2019-04-29 /pmc/articles/PMC6849732/ /pubmed/30903806 http://dx.doi.org/10.1111/mcn.12817 Text en © 2019 John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Isanaka, Sheila
Hitchings, Matt D.T.
Berthé, Fatou
Briend, André
Grais, Rebecca F.
Linear growth faltering and the role of weight attainment: Prospective analysis of young children recovering from severe wasting in Niger
title Linear growth faltering and the role of weight attainment: Prospective analysis of young children recovering from severe wasting in Niger
title_full Linear growth faltering and the role of weight attainment: Prospective analysis of young children recovering from severe wasting in Niger
title_fullStr Linear growth faltering and the role of weight attainment: Prospective analysis of young children recovering from severe wasting in Niger
title_full_unstemmed Linear growth faltering and the role of weight attainment: Prospective analysis of young children recovering from severe wasting in Niger
title_short Linear growth faltering and the role of weight attainment: Prospective analysis of young children recovering from severe wasting in Niger
title_sort linear growth faltering and the role of weight attainment: prospective analysis of young children recovering from severe wasting in niger
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849732/
https://www.ncbi.nlm.nih.gov/pubmed/30903806
http://dx.doi.org/10.1111/mcn.12817
work_keys_str_mv AT isanakasheila lineargrowthfalteringandtheroleofweightattainmentprospectiveanalysisofyoungchildrenrecoveringfromseverewastinginniger
AT hitchingsmattdt lineargrowthfalteringandtheroleofweightattainmentprospectiveanalysisofyoungchildrenrecoveringfromseverewastinginniger
AT berthefatou lineargrowthfalteringandtheroleofweightattainmentprospectiveanalysisofyoungchildrenrecoveringfromseverewastinginniger
AT briendandre lineargrowthfalteringandtheroleofweightattainmentprospectiveanalysisofyoungchildrenrecoveringfromseverewastinginniger
AT graisrebeccaf lineargrowthfalteringandtheroleofweightattainmentprospectiveanalysisofyoungchildrenrecoveringfromseverewastinginniger