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Urate‐lowering therapy alleviates atherosclerosis inflammatory response factors and neointimal lesions in a mouse model of induced carotid atherosclerosis

Hyperuricemia (HU) is a cause of gout. Clinical studies show a link between HU and cardiovascular disease. However, the role of soluble serum urate (SU) on atherosclerosis development remains elusive. We aimed to use a new HU mouse model [Uricase/Uox knockout (KO)] to further investigate the relatio...

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Detalles Bibliográficos
Autores principales:	Lu, Jie, Sun, Mingshu, Wu, Xinjiang, Yuan, Xuan, Liu, Zhen, Qu, Xiaojie, Ji, Xiaopeng, Merriman, Tony R., Li, Changgui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849826/ https://www.ncbi.nlm.nih.gov/pubmed/30690853 http://dx.doi.org/10.1111/febs.14768

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