The direct oral anticoagulants rivaroxaban and dabigatran do not inhibit orthotopic growth and metastasis of human breast cancer in mice

ESSENTIALS: Factor Xa (FXa)‐targeting direct oral anticoagulants (DOACs) reduce venous thromboembolism (VTE). The effects of FXa‐targeting DOACs on cancer progression remain to be studied. In xenograft models, a FXa‐targeting DOAC did not inhibit breast cancer growth and metastasis. A thrombin‐targe...

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Detalles Bibliográficos
Autores principales: Buijs, Jeroen T., Laghmani, El H., van den Akker, Rob F. P., Tieken, Chris, Vletter, Esther M., van der Molen, Kim M., Crooijmans, Juliette J., Kroone, Chantal, Le Dévédec, Sylvia E., van der Pluijm, Gabri, Versteeg, Henri H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
HAEMOSTASIS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849835/
https://www.ncbi.nlm.nih.gov/pubmed/30929299
http://dx.doi.org/10.1111/jth.14443

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