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Long‐term follow‐up of a multicentre cohort study on laparoscopic peritoneal lavage for perforated diverticulitis

AIM: Laparoscopic peritoneal lavage has increasingly been investigated as a promising alternative to sigmoidectomy for perforated diverticulitis with purulent peritonitis. Most studies only reported outcomes up to 12 months. Therefore, the objective of this study was to evaluate long‐term outcomes o...

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Autores principales: Sneiders, D., Lambrichts, D. P. V., Swank, H. A., Blanken‐Peeters, C. F. J. M., Nienhuijs, S. W., Govaert, M. J. P. M., Gerhards, M. F., Hoofwijk, A. G. M., Bosker, R. J. I., van der Bilt, J. D. W., Heijnen, B. H. M., ten Cate Hoedemaker, H. O., Kleinrensink, G. J., Lange, J. F., Bemelman, W. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850083/
https://www.ncbi.nlm.nih.gov/pubmed/30771246
http://dx.doi.org/10.1111/codi.14586
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author Sneiders, D.
Lambrichts, D. P. V.
Swank, H. A.
Blanken‐Peeters, C. F. J. M.
Nienhuijs, S. W.
Govaert, M. J. P. M.
Gerhards, M. F.
Hoofwijk, A. G. M.
Bosker, R. J. I.
van der Bilt, J. D. W.
Heijnen, B. H. M.
ten Cate Hoedemaker, H. O.
Kleinrensink, G. J.
Lange, J. F.
Bemelman, W. A.
author_facet Sneiders, D.
Lambrichts, D. P. V.
Swank, H. A.
Blanken‐Peeters, C. F. J. M.
Nienhuijs, S. W.
Govaert, M. J. P. M.
Gerhards, M. F.
Hoofwijk, A. G. M.
Bosker, R. J. I.
van der Bilt, J. D. W.
Heijnen, B. H. M.
ten Cate Hoedemaker, H. O.
Kleinrensink, G. J.
Lange, J. F.
Bemelman, W. A.
author_sort Sneiders, D.
collection PubMed
description AIM: Laparoscopic peritoneal lavage has increasingly been investigated as a promising alternative to sigmoidectomy for perforated diverticulitis with purulent peritonitis. Most studies only reported outcomes up to 12 months. Therefore, the objective of this study was to evaluate long‐term outcomes of patients treated with laparoscopic lavage. METHODS: Between 2008 and 2010, 38 patients treated with laparoscopic lavage for perforated diverticulitis in 10 Dutch teaching hospitals were included. Long‐term follow‐up data on patient outcomes, e.g. diverticulitis recurrence, reoperations and readmissions, were collected retrospectively. The characteristics of patients with recurrent diverticulitis or complications requiring surgery or leading to death, categorized as ‘overall complicated outcome’, were compared with patients who developed no complications or complications not requiring surgery. RESULTS: The median follow‐up was 46 months (interquartile range 7–77), during which 17 episodes of recurrent diverticulitis (seven complicated) in 12 patients (32%) occurred. Twelve patients (32%) required additional surgery with a total of 29 procedures. Fifteen patients (39%) had a total of 50 readmissions. Of initially successfully treated patients (n = 31), 12 (31%) had recurrent diverticulitis or other complications. At 90 days, 32 (84%) patients were alive without undergoing a sigmoidectomy. However, seven (22%) of these patients eventually had a sigmoidectomy after 90 days. Diverticulitis‐related events occurred up to 6 years after the index procedure. CONCLUSION: Long‐term diverticulitis recurrence, re‐intervention and readmission rates after laparoscopic lavage were high. A complicated outcome was also seen in patients who had initially been treated successfully with laparoscopic lavage with relevant events occurring up to 6 years after initial surgery.
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spelling pubmed-68500832019-11-15 Long‐term follow‐up of a multicentre cohort study on laparoscopic peritoneal lavage for perforated diverticulitis Sneiders, D. Lambrichts, D. P. V. Swank, H. A. Blanken‐Peeters, C. F. J. M. Nienhuijs, S. W. Govaert, M. J. P. M. Gerhards, M. F. Hoofwijk, A. G. M. Bosker, R. J. I. van der Bilt, J. D. W. Heijnen, B. H. M. ten Cate Hoedemaker, H. O. Kleinrensink, G. J. Lange, J. F. Bemelman, W. A. Colorectal Dis Original Articles AIM: Laparoscopic peritoneal lavage has increasingly been investigated as a promising alternative to sigmoidectomy for perforated diverticulitis with purulent peritonitis. Most studies only reported outcomes up to 12 months. Therefore, the objective of this study was to evaluate long‐term outcomes of patients treated with laparoscopic lavage. METHODS: Between 2008 and 2010, 38 patients treated with laparoscopic lavage for perforated diverticulitis in 10 Dutch teaching hospitals were included. Long‐term follow‐up data on patient outcomes, e.g. diverticulitis recurrence, reoperations and readmissions, were collected retrospectively. The characteristics of patients with recurrent diverticulitis or complications requiring surgery or leading to death, categorized as ‘overall complicated outcome’, were compared with patients who developed no complications or complications not requiring surgery. RESULTS: The median follow‐up was 46 months (interquartile range 7–77), during which 17 episodes of recurrent diverticulitis (seven complicated) in 12 patients (32%) occurred. Twelve patients (32%) required additional surgery with a total of 29 procedures. Fifteen patients (39%) had a total of 50 readmissions. Of initially successfully treated patients (n = 31), 12 (31%) had recurrent diverticulitis or other complications. At 90 days, 32 (84%) patients were alive without undergoing a sigmoidectomy. However, seven (22%) of these patients eventually had a sigmoidectomy after 90 days. Diverticulitis‐related events occurred up to 6 years after the index procedure. CONCLUSION: Long‐term diverticulitis recurrence, re‐intervention and readmission rates after laparoscopic lavage were high. A complicated outcome was also seen in patients who had initially been treated successfully with laparoscopic lavage with relevant events occurring up to 6 years after initial surgery. John Wiley and Sons Inc. 2019-03-07 2019-06 /pmc/articles/PMC6850083/ /pubmed/30771246 http://dx.doi.org/10.1111/codi.14586 Text en © 2019 The Authors. Colorectal Disease published by John Wiley & Sons Ltd on behalf of Association of Coloproctology of Great Britain and Ireland This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Sneiders, D.
Lambrichts, D. P. V.
Swank, H. A.
Blanken‐Peeters, C. F. J. M.
Nienhuijs, S. W.
Govaert, M. J. P. M.
Gerhards, M. F.
Hoofwijk, A. G. M.
Bosker, R. J. I.
van der Bilt, J. D. W.
Heijnen, B. H. M.
ten Cate Hoedemaker, H. O.
Kleinrensink, G. J.
Lange, J. F.
Bemelman, W. A.
Long‐term follow‐up of a multicentre cohort study on laparoscopic peritoneal lavage for perforated diverticulitis
title Long‐term follow‐up of a multicentre cohort study on laparoscopic peritoneal lavage for perforated diverticulitis
title_full Long‐term follow‐up of a multicentre cohort study on laparoscopic peritoneal lavage for perforated diverticulitis
title_fullStr Long‐term follow‐up of a multicentre cohort study on laparoscopic peritoneal lavage for perforated diverticulitis
title_full_unstemmed Long‐term follow‐up of a multicentre cohort study on laparoscopic peritoneal lavage for perforated diverticulitis
title_short Long‐term follow‐up of a multicentre cohort study on laparoscopic peritoneal lavage for perforated diverticulitis
title_sort long‐term follow‐up of a multicentre cohort study on laparoscopic peritoneal lavage for perforated diverticulitis
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850083/
https://www.ncbi.nlm.nih.gov/pubmed/30771246
http://dx.doi.org/10.1111/codi.14586
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