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Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte
Remodeling of the gene regulatory network in cells is believed to be a prerequisite for their lineage reprogramming. However, its key regulatory factors are not yet elucidated. In this article, we investigate the role of PIWI proteins and provide evidence that one of them, MIWI2, is elicited during...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850183/ https://www.ncbi.nlm.nih.gov/pubmed/30805989 http://dx.doi.org/10.1002/stem.2994 |