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Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte

Remodeling of the gene regulatory network in cells is believed to be a prerequisite for their lineage reprogramming. However, its key regulatory factors are not yet elucidated. In this article, we investigate the role of PIWI proteins and provide evidence that one of them, MIWI2, is elicited during...

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Detalles Bibliográficos
Autores principales: Shi, Xiaojie, Xiao, Zipei, Zonta, Francesco, Wang, Wei, Wan, Yue, Li, Yu, Wang, Nan, Kuang, Yuanyuan, Du, Mingjuan, Dong, Jian, Wang, Ju, Yang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850183/
https://www.ncbi.nlm.nih.gov/pubmed/30805989
http://dx.doi.org/10.1002/stem.2994