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Sirtilins – the new old members of the vitamin K‐dependent coagulation factor family

ESSENTIALS: Blood coagulation is driven by vitamin K (VK)‐dependent proteases. We have identified and characterized ‘sirtilin’ as an additional VK‐dependent protease. Sirtilins emerged early in the evolution of the coagulation system of vertebrates. Ubiquitous occurrence might indicate an important...

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Detalles Bibliográficos
Autores principales: Dahms, Sven O., Demir, Fatih, Huesgen, Pitter F., Thorn, Karina, Brandstetter, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850207/
https://www.ncbi.nlm.nih.gov/pubmed/30644641
http://dx.doi.org/10.1111/jth.14384

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