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A rare case of chronic otitis externa due to Mycobacterium tuberculosis

Chronic otitis externa due to Mycobacterium tuberculosis complex is extremely rare and very few cases have been presented in the medical literature. We report here the case of an immunocompetent 68-year-old male with chronic auricular drainage, otalgia, hearing loss, external ear canal and tympanic...

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Autores principales: DeSimone, Daniel C., Heaton, Philip R., Neff, Brian A., Dao, Linda N., Wengenack, Nancy L., Fadel, Hind J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850261/
https://www.ncbi.nlm.nih.gov/pubmed/31723705
http://dx.doi.org/10.1016/j.jctube.2017.05.001
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author DeSimone, Daniel C.
Heaton, Philip R.
Neff, Brian A.
Dao, Linda N.
Wengenack, Nancy L.
Fadel, Hind J.
author_facet DeSimone, Daniel C.
Heaton, Philip R.
Neff, Brian A.
Dao, Linda N.
Wengenack, Nancy L.
Fadel, Hind J.
author_sort DeSimone, Daniel C.
collection PubMed
description Chronic otitis externa due to Mycobacterium tuberculosis complex is extremely rare and very few cases have been presented in the medical literature. We report here the case of an immunocompetent 68-year-old male with chronic auricular drainage, otalgia, hearing loss, external ear canal and tympanic membrane thickening for 3 years who was ultimately diagnosed with tuberculous chronic otitis externa on biopsy of external auditory canal granulation tissue using molecular diagnostic techniques. Later, sputum cultures were positive for Mycobacterium tuberculosis complex indicating disseminated tuberculosis. However, two plausible explanations could be pulmonary TB that disseminated to the ear canal with evidence of middle and outer otitis, or upper airway/nasopharyngeal involvement with direct extension into the middle and outer ear canals. Although extremely rare, extrapulmonary laryngeal head and neck tuberculosis should be considered in immunocompetent patients who present with chronic otitis without prior known exposure to tuberculosis when they fail standard therapy and in whom no other microbiologic cause can be identified.
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spelling pubmed-68502612019-11-13 A rare case of chronic otitis externa due to Mycobacterium tuberculosis DeSimone, Daniel C. Heaton, Philip R. Neff, Brian A. Dao, Linda N. Wengenack, Nancy L. Fadel, Hind J. J Clin Tuberc Other Mycobact Dis Article Chronic otitis externa due to Mycobacterium tuberculosis complex is extremely rare and very few cases have been presented in the medical literature. We report here the case of an immunocompetent 68-year-old male with chronic auricular drainage, otalgia, hearing loss, external ear canal and tympanic membrane thickening for 3 years who was ultimately diagnosed with tuberculous chronic otitis externa on biopsy of external auditory canal granulation tissue using molecular diagnostic techniques. Later, sputum cultures were positive for Mycobacterium tuberculosis complex indicating disseminated tuberculosis. However, two plausible explanations could be pulmonary TB that disseminated to the ear canal with evidence of middle and outer otitis, or upper airway/nasopharyngeal involvement with direct extension into the middle and outer ear canals. Although extremely rare, extrapulmonary laryngeal head and neck tuberculosis should be considered in immunocompetent patients who present with chronic otitis without prior known exposure to tuberculosis when they fail standard therapy and in whom no other microbiologic cause can be identified. Elsevier 2017-05-16 /pmc/articles/PMC6850261/ /pubmed/31723705 http://dx.doi.org/10.1016/j.jctube.2017.05.001 Text en © 2017 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
DeSimone, Daniel C.
Heaton, Philip R.
Neff, Brian A.
Dao, Linda N.
Wengenack, Nancy L.
Fadel, Hind J.
A rare case of chronic otitis externa due to Mycobacterium tuberculosis
title A rare case of chronic otitis externa due to Mycobacterium tuberculosis
title_full A rare case of chronic otitis externa due to Mycobacterium tuberculosis
title_fullStr A rare case of chronic otitis externa due to Mycobacterium tuberculosis
title_full_unstemmed A rare case of chronic otitis externa due to Mycobacterium tuberculosis
title_short A rare case of chronic otitis externa due to Mycobacterium tuberculosis
title_sort rare case of chronic otitis externa due to mycobacterium tuberculosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850261/
https://www.ncbi.nlm.nih.gov/pubmed/31723705
http://dx.doi.org/10.1016/j.jctube.2017.05.001
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