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Anatomical site variation of water content in human skin measured by the Epsilon: A pilot study

BACKGROUND: This pilot study aimed to investigate the anatomical site variation of water content of the stratum corneum (SC) on the body by measuring skin capacitance with the Epsilon, a new generation corneometer with multiple sensors. Secondly, values of the Epsilon were compared to values measure...

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Autores principales: Logger, Jade G. M., Münchhoff, Christina U., Olydam, Jill I., Peppelman, Malou, Van Erp, Piet E. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850423/
https://www.ncbi.nlm.nih.gov/pubmed/30604523
http://dx.doi.org/10.1111/srt.12653
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author Logger, Jade G. M.
Münchhoff, Christina U.
Olydam, Jill I.
Peppelman, Malou
Van Erp, Piet E. J.
author_facet Logger, Jade G. M.
Münchhoff, Christina U.
Olydam, Jill I.
Peppelman, Malou
Van Erp, Piet E. J.
author_sort Logger, Jade G. M.
collection PubMed
description BACKGROUND: This pilot study aimed to investigate the anatomical site variation of water content of the stratum corneum (SC) on the body by measuring skin capacitance with the Epsilon, a new generation corneometer with multiple sensors. Secondly, values of the Epsilon were compared to values measured by conventional single sensor corneometers. METHODS: The hydration status of SC was measured in 15 healthy Caucasian volunteers with the Epsilon at five body sites (cheek, lower forearm, mid‐calf, lower back and abdomen). Transepidermal water loss (TEWL) was measured with the Aquaflux to get more insight into the condition of the skin barrier. A literature search was performed to compare Epsilon values with conventional corneometers. RESULTS: The tested anatomical locations showed significant differences in water content (P < 0.001) with large interindividual variations; highest values were found in the cheek (11.64ε) and lowest values in the mid‐calf (4.43ε). No correlation between water content and TEWL was found. In general, Epsilon values were lower compared to values of conventional corneometers, with a similar trend. CONCLUSION: This pilot study showed significant variations in water content at different skin locations measured by the Epsilon. Moreover, the Epsilon measured consistent lower values compared to single sensor corneometers. Further validation of the device is recommended.
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spelling pubmed-68504232019-11-18 Anatomical site variation of water content in human skin measured by the Epsilon: A pilot study Logger, Jade G. M. Münchhoff, Christina U. Olydam, Jill I. Peppelman, Malou Van Erp, Piet E. J. Skin Res Technol Original Articles BACKGROUND: This pilot study aimed to investigate the anatomical site variation of water content of the stratum corneum (SC) on the body by measuring skin capacitance with the Epsilon, a new generation corneometer with multiple sensors. Secondly, values of the Epsilon were compared to values measured by conventional single sensor corneometers. METHODS: The hydration status of SC was measured in 15 healthy Caucasian volunteers with the Epsilon at five body sites (cheek, lower forearm, mid‐calf, lower back and abdomen). Transepidermal water loss (TEWL) was measured with the Aquaflux to get more insight into the condition of the skin barrier. A literature search was performed to compare Epsilon values with conventional corneometers. RESULTS: The tested anatomical locations showed significant differences in water content (P < 0.001) with large interindividual variations; highest values were found in the cheek (11.64ε) and lowest values in the mid‐calf (4.43ε). No correlation between water content and TEWL was found. In general, Epsilon values were lower compared to values of conventional corneometers, with a similar trend. CONCLUSION: This pilot study showed significant variations in water content at different skin locations measured by the Epsilon. Moreover, the Epsilon measured consistent lower values compared to single sensor corneometers. Further validation of the device is recommended. John Wiley and Sons Inc. 2019-01-03 2019-05 /pmc/articles/PMC6850423/ /pubmed/30604523 http://dx.doi.org/10.1111/srt.12653 Text en © 2019 The Authors. Skin Research and Technology Published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Logger, Jade G. M.
Münchhoff, Christina U.
Olydam, Jill I.
Peppelman, Malou
Van Erp, Piet E. J.
Anatomical site variation of water content in human skin measured by the Epsilon: A pilot study
title Anatomical site variation of water content in human skin measured by the Epsilon: A pilot study
title_full Anatomical site variation of water content in human skin measured by the Epsilon: A pilot study
title_fullStr Anatomical site variation of water content in human skin measured by the Epsilon: A pilot study
title_full_unstemmed Anatomical site variation of water content in human skin measured by the Epsilon: A pilot study
title_short Anatomical site variation of water content in human skin measured by the Epsilon: A pilot study
title_sort anatomical site variation of water content in human skin measured by the epsilon: a pilot study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850423/
https://www.ncbi.nlm.nih.gov/pubmed/30604523
http://dx.doi.org/10.1111/srt.12653
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