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Targeting anaplastic lymphoma kinase in neuroblastoma

Over the last decade, anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase (RTK), has been identified as a fusion partner in a diverse variety of translocation events resulting in oncogenic signaling in many different cancer types. In tumors where the full‐length ALK RTK itself is mutated, s...

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Detalles Bibliográficos
Autores principales: Umapathy, Ganesh, Mendoza‐Garcia, Patricia, Hallberg, Bengt, Palmer, Ruth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850425/
https://www.ncbi.nlm.nih.gov/pubmed/30803032
http://dx.doi.org/10.1111/apm.12940