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Regulation of mitochondrial ROS production by HIC‐5: a common feature of oncogene‐induced senescence and tumor invasiveness?
Transformation by the ras oncogene can result in promotion of metastasis as well as induction of senescence via increased tissue remodeling, for example, by matrix metalloproteases. Increased production of mitochondrial reactive oxygen species (mtROS) via NADPH oxidase 4 (NOX4) is implicated in this...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850634/ https://www.ncbi.nlm.nih.gov/pubmed/30680933 http://dx.doi.org/10.1111/febs.14746 |