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Leadless pacemaker implant in patients with pre‐existing infections: Results from the Micra postapproval registry
INTRODUCTION: Leadless pacemakers may provide a safe and attractive pacing option to patients with cardiac implantable electronic device (CIED) infection. We describe the characteristics and outcomes of patients with a recent CIED infection undergoing Micra implant attempt. METHODS AND RESULTS: Pati...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850680/ https://www.ncbi.nlm.nih.gov/pubmed/30661279 http://dx.doi.org/10.1111/jce.13851 |
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author | El‐Chami, Mikhael F. Johansen, Jens Brock Zaidi, Amir Faerestrand, Svein Reynolds, Dwight Garcia‐Seara, Javier Mansourati, Jacques Pasquie, Jean‐Luc McElderry, Hugh Thomas Roberts, Paul R. Soejima, Kyoko Stromberg, Kurt Piccini, Jonathan P. |
author_facet | El‐Chami, Mikhael F. Johansen, Jens Brock Zaidi, Amir Faerestrand, Svein Reynolds, Dwight Garcia‐Seara, Javier Mansourati, Jacques Pasquie, Jean‐Luc McElderry, Hugh Thomas Roberts, Paul R. Soejima, Kyoko Stromberg, Kurt Piccini, Jonathan P. |
author_sort | El‐Chami, Mikhael F. |
collection | PubMed |
description | INTRODUCTION: Leadless pacemakers may provide a safe and attractive pacing option to patients with cardiac implantable electronic device (CIED) infection. We describe the characteristics and outcomes of patients with a recent CIED infection undergoing Micra implant attempt. METHODS AND RESULTS: Patients with prior CIED infection and device explant with Micra implant within 30 days, were identified from the Micra post approval registry. Procedure characteristics and outcomes were summarized. A total of 105 patients with prior CIED infection underwent Micra implant attempt ≤30 days from prior system explant (84 [80%] pacemakers and 13 [12%] ICD/CRT‐D). All system components were explanted in 93% of patients and explant occurred a median of 6 days before Micra implant, with 37% occurring on the day of Micra implant. Micra was successfully implanted in 99% patients, mean follow‐up duration was 8.5 ± 7.1 months (range 0‐28.5). The majority of patients (91%) received IV antibiotics preimplant, while 42% of patients received IV antibiotics postprocedure. The median length of hospitalization following Micra implant was 2 days (IQR, 1‐7). During follow‐up, two patients died from sepsis and four patients required system upgrade, of which two patients received Micra to provide temporary pacing support. There were no Micra devices explanted due to infection. CONCLUSION: Implantation of the Micra transcatheter pacemaker is safe and feasible in patients with a recent CIED infection. No recurrent infections that required Micra device removal were seen. Leadless pacemakers appear to be a safe pacing alternative for patients with CIED infection who undergo extraction. |
format | Online Article Text |
id | pubmed-6850680 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-68506802019-11-18 Leadless pacemaker implant in patients with pre‐existing infections: Results from the Micra postapproval registry El‐Chami, Mikhael F. Johansen, Jens Brock Zaidi, Amir Faerestrand, Svein Reynolds, Dwight Garcia‐Seara, Javier Mansourati, Jacques Pasquie, Jean‐Luc McElderry, Hugh Thomas Roberts, Paul R. Soejima, Kyoko Stromberg, Kurt Piccini, Jonathan P. J Cardiovasc Electrophysiol Original Articles INTRODUCTION: Leadless pacemakers may provide a safe and attractive pacing option to patients with cardiac implantable electronic device (CIED) infection. We describe the characteristics and outcomes of patients with a recent CIED infection undergoing Micra implant attempt. METHODS AND RESULTS: Patients with prior CIED infection and device explant with Micra implant within 30 days, were identified from the Micra post approval registry. Procedure characteristics and outcomes were summarized. A total of 105 patients with prior CIED infection underwent Micra implant attempt ≤30 days from prior system explant (84 [80%] pacemakers and 13 [12%] ICD/CRT‐D). All system components were explanted in 93% of patients and explant occurred a median of 6 days before Micra implant, with 37% occurring on the day of Micra implant. Micra was successfully implanted in 99% patients, mean follow‐up duration was 8.5 ± 7.1 months (range 0‐28.5). The majority of patients (91%) received IV antibiotics preimplant, while 42% of patients received IV antibiotics postprocedure. The median length of hospitalization following Micra implant was 2 days (IQR, 1‐7). During follow‐up, two patients died from sepsis and four patients required system upgrade, of which two patients received Micra to provide temporary pacing support. There were no Micra devices explanted due to infection. CONCLUSION: Implantation of the Micra transcatheter pacemaker is safe and feasible in patients with a recent CIED infection. No recurrent infections that required Micra device removal were seen. Leadless pacemakers appear to be a safe pacing alternative for patients with CIED infection who undergo extraction. John Wiley and Sons Inc. 2019-01-28 2019-04 /pmc/articles/PMC6850680/ /pubmed/30661279 http://dx.doi.org/10.1111/jce.13851 Text en © 2019 The Authors. Journal of Cardiovascular Electrophysiology Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles El‐Chami, Mikhael F. Johansen, Jens Brock Zaidi, Amir Faerestrand, Svein Reynolds, Dwight Garcia‐Seara, Javier Mansourati, Jacques Pasquie, Jean‐Luc McElderry, Hugh Thomas Roberts, Paul R. Soejima, Kyoko Stromberg, Kurt Piccini, Jonathan P. Leadless pacemaker implant in patients with pre‐existing infections: Results from the Micra postapproval registry |
title | Leadless pacemaker implant in patients with pre‐existing infections: Results from the Micra postapproval registry |
title_full | Leadless pacemaker implant in patients with pre‐existing infections: Results from the Micra postapproval registry |
title_fullStr | Leadless pacemaker implant in patients with pre‐existing infections: Results from the Micra postapproval registry |
title_full_unstemmed | Leadless pacemaker implant in patients with pre‐existing infections: Results from the Micra postapproval registry |
title_short | Leadless pacemaker implant in patients with pre‐existing infections: Results from the Micra postapproval registry |
title_sort | leadless pacemaker implant in patients with pre‐existing infections: results from the micra postapproval registry |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850680/ https://www.ncbi.nlm.nih.gov/pubmed/30661279 http://dx.doi.org/10.1111/jce.13851 |
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