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Relationship between occupational sunlight exposure and the incidence of renal cancer
BACKGROUND: The risk factors for renal cancer include smoking, obesity, hypertension, and exposure to trichloroethylene. Recent studies have shown that low sunlight exposure increases the risk of developing a range of cancers, including renal cancer. Given that most of the daytime is spent at work,...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Occupational & Environmental Medicine
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850789/ https://www.ncbi.nlm.nih.gov/pubmed/31737287 http://dx.doi.org/10.35371/aoem.2019.31.e32 |
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author | Jang, Hyun-Suk Leem, Jong-Han Jeon, Seong Soo Park, Shin-Goo Lee, Sangyoon Kang, Yangwon Choi, Go Kim, Hyung Doo Ju, Hyeonwoo Jang, Sung Wook Won, Youna Kim, Hwan-Cheol |
author_facet | Jang, Hyun-Suk Leem, Jong-Han Jeon, Seong Soo Park, Shin-Goo Lee, Sangyoon Kang, Yangwon Choi, Go Kim, Hyung Doo Ju, Hyeonwoo Jang, Sung Wook Won, Youna Kim, Hwan-Cheol |
author_sort | Jang, Hyun-Suk |
collection | PubMed |
description | BACKGROUND: The risk factors for renal cancer include smoking, obesity, hypertension, and exposure to trichloroethylene. Recent studies have shown that low sunlight exposure increases the risk of developing a range of cancers, including renal cancer. Given that most of the daytime is spent at work, a lack of occupational sunlight exposure can be a risk factor for renal cancer. Therefore, this study examined the relationship between occupational sunlight exposure and the incidence of renal cancer. METHODS: This was a university hospital-based case-control study on renal cancer. Of the 706 newly diagnosed patients with renal cell carcinoma (RCC), 633 cases were selected; 73 who had no occupational history were excluded. In addition, 633 controls were selected from the general population after 1:1 matching with respect to sex, age (within 5 years), and residential area (constituency-level). Information on sunlight exposure by the occupational group was referred to data from France. To estimate the association between occupational sunlight exposure and the RCC risk, the odds ratios (ORs) were calculated using conditional logistic regression analysis. RESULTS: Sunlight exposure was divided into quartiles and the risk of RCC was analyzed. The adjusted OR of RCC (OR: 0.664, 95% confidence interval: 0.449–0.983) was significantly lower for the Q4 group than Q1 group but the Q2 and Q3 groups did not show significant results. The risk of RCC tended to decrease with increasing exposure to sunlight (p for trend < 0.028). CONCLUSIONS: Higher occupational sunlight exposure reduces the risk of RCC. |
format | Online Article Text |
id | pubmed-6850789 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Korean Society of Occupational & Environmental Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-68507892019-11-16 Relationship between occupational sunlight exposure and the incidence of renal cancer Jang, Hyun-Suk Leem, Jong-Han Jeon, Seong Soo Park, Shin-Goo Lee, Sangyoon Kang, Yangwon Choi, Go Kim, Hyung Doo Ju, Hyeonwoo Jang, Sung Wook Won, Youna Kim, Hwan-Cheol Ann Occup Environ Med Research Article BACKGROUND: The risk factors for renal cancer include smoking, obesity, hypertension, and exposure to trichloroethylene. Recent studies have shown that low sunlight exposure increases the risk of developing a range of cancers, including renal cancer. Given that most of the daytime is spent at work, a lack of occupational sunlight exposure can be a risk factor for renal cancer. Therefore, this study examined the relationship between occupational sunlight exposure and the incidence of renal cancer. METHODS: This was a university hospital-based case-control study on renal cancer. Of the 706 newly diagnosed patients with renal cell carcinoma (RCC), 633 cases were selected; 73 who had no occupational history were excluded. In addition, 633 controls were selected from the general population after 1:1 matching with respect to sex, age (within 5 years), and residential area (constituency-level). Information on sunlight exposure by the occupational group was referred to data from France. To estimate the association between occupational sunlight exposure and the RCC risk, the odds ratios (ORs) were calculated using conditional logistic regression analysis. RESULTS: Sunlight exposure was divided into quartiles and the risk of RCC was analyzed. The adjusted OR of RCC (OR: 0.664, 95% confidence interval: 0.449–0.983) was significantly lower for the Q4 group than Q1 group but the Q2 and Q3 groups did not show significant results. The risk of RCC tended to decrease with increasing exposure to sunlight (p for trend < 0.028). CONCLUSIONS: Higher occupational sunlight exposure reduces the risk of RCC. Korean Society of Occupational & Environmental Medicine 2019-11-07 /pmc/articles/PMC6850789/ /pubmed/31737287 http://dx.doi.org/10.35371/aoem.2019.31.e32 Text en Copyright © 2019 Korean Society of Occupational & Environmental Medicine https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Jang, Hyun-Suk Leem, Jong-Han Jeon, Seong Soo Park, Shin-Goo Lee, Sangyoon Kang, Yangwon Choi, Go Kim, Hyung Doo Ju, Hyeonwoo Jang, Sung Wook Won, Youna Kim, Hwan-Cheol Relationship between occupational sunlight exposure and the incidence of renal cancer |
title | Relationship between occupational sunlight exposure and the incidence of renal cancer |
title_full | Relationship between occupational sunlight exposure and the incidence of renal cancer |
title_fullStr | Relationship between occupational sunlight exposure and the incidence of renal cancer |
title_full_unstemmed | Relationship between occupational sunlight exposure and the incidence of renal cancer |
title_short | Relationship between occupational sunlight exposure and the incidence of renal cancer |
title_sort | relationship between occupational sunlight exposure and the incidence of renal cancer |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850789/ https://www.ncbi.nlm.nih.gov/pubmed/31737287 http://dx.doi.org/10.35371/aoem.2019.31.e32 |
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