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A novel single‐chain enzyme complex with chain reaction properties rapidly producing thromboxane A(2) and exhibiting powerful anti‐bleeding functions
Uncontrollable bleeding is still a worldwide killer. In this study, we aimed to investigate a novel approach to exhibit effective haemostatic properties, which could possibly save lives in various bleeding emergencies. According to the structure‐based enzymatic design, we have engineered a novel sin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850917/ https://www.ncbi.nlm.nih.gov/pubmed/31628732 http://dx.doi.org/10.1111/jcmm.14711 |