Developments in cell culture systems for human pluripotent stem cells

Human pluripotent stem cells (hPSCs) are important resources for cell-based therapies and pharmaceutical applications. In order to realize the potential of hPSCs, it is critical to develop suitable technologies required for specific applications. Most hPSC technologies depend on cell culture, and ar...

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Detalles Bibliográficos
Autores principales: Liu, Weiwei, Deng, Chunhao, Godoy-Parejo, Carlos, Zhang, Yumeng, Chen, Guokai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851012/
https://www.ncbi.nlm.nih.gov/pubmed/31768223
http://dx.doi.org/10.4252/wjsc.v11.i11.968
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author Liu, Weiwei
Deng, Chunhao
Godoy-Parejo, Carlos
Zhang, Yumeng
Chen, Guokai
author_facet Liu, Weiwei
Deng, Chunhao
Godoy-Parejo, Carlos
Zhang, Yumeng
Chen, Guokai
author_sort Liu, Weiwei
collection PubMed
description Human pluripotent stem cells (hPSCs) are important resources for cell-based therapies and pharmaceutical applications. In order to realize the potential of hPSCs, it is critical to develop suitable technologies required for specific applications. Most hPSC technologies depend on cell culture, and are critically influenced by culture medium composition, extracellular matrices, handling methods, and culture platforms. This review summarizes the major technological advances in hPSC culture, and highlights the opportunities and challenges in future therapeutic applications.
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spelling pubmed-68510122019-11-26 Developments in cell culture systems for human pluripotent stem cells Liu, Weiwei Deng, Chunhao Godoy-Parejo, Carlos Zhang, Yumeng Chen, Guokai World J Stem Cells Review Human pluripotent stem cells (hPSCs) are important resources for cell-based therapies and pharmaceutical applications. In order to realize the potential of hPSCs, it is critical to develop suitable technologies required for specific applications. Most hPSC technologies depend on cell culture, and are critically influenced by culture medium composition, extracellular matrices, handling methods, and culture platforms. This review summarizes the major technological advances in hPSC culture, and highlights the opportunities and challenges in future therapeutic applications. Baishideng Publishing Group Inc 2019-11-26 2019-11-26 /pmc/articles/PMC6851012/ /pubmed/31768223 http://dx.doi.org/10.4252/wjsc.v11.i11.968 Text en ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Review
Liu, Weiwei
Deng, Chunhao
Godoy-Parejo, Carlos
Zhang, Yumeng
Chen, Guokai
Developments in cell culture systems for human pluripotent stem cells
title Developments in cell culture systems for human pluripotent stem cells
title_full Developments in cell culture systems for human pluripotent stem cells
title_fullStr Developments in cell culture systems for human pluripotent stem cells
title_full_unstemmed Developments in cell culture systems for human pluripotent stem cells
title_short Developments in cell culture systems for human pluripotent stem cells
title_sort developments in cell culture systems for human pluripotent stem cells
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851012/
https://www.ncbi.nlm.nih.gov/pubmed/31768223
http://dx.doi.org/10.4252/wjsc.v11.i11.968
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AT zhangyumeng developmentsincellculturesystemsforhumanpluripotentstemcells
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