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Reduced Expression of PLCXD3 Associates With Disruption of Glucose Sensing and Insulin Signaling in Pancreatic β-Cells

Previous work has shown that reduced expression of PLCXD3, a member of the phosphoinositide-specific phospholipases (PI-PLC) family, impaired insulin secretion with an unclear mechanism. In the current study, we aim to investigate the mechanism underlying this effect using human islets and rat INS-1...

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Detalles Bibliográficos
Autores principales:	Aljaibeji, Hayat, Mukhopadhyay, Debasmita, Mohammed, Abdul Khader, Dhaiban, Sarah, Hachim, Mahmood Y., Elemam, Noha M., Sulaiman, Nabil, Salehi, Albert, Taneera, Jalal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851018/ https://www.ncbi.nlm.nih.gov/pubmed/31781030 http://dx.doi.org/10.3389/fendo.2019.00735

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