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Gene Expression-Based Identification of Antigen-Responsive CD8(+) T Cells on a Single-Cell Level
CD8(+) T cells are important effectors of adaptive immunity against pathogens, tumors, and self antigens. Here, we asked how human cognate antigen-responsive CD8(+) T cells and their receptors could be identified in unselected single-cell gene expression data. Single-cell RNA sequencing and qPCR of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851025/ https://www.ncbi.nlm.nih.gov/pubmed/31781096 http://dx.doi.org/10.3389/fimmu.2019.02568 |