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Gene Expression-Based Identification of Antigen-Responsive CD8(+) T Cells on a Single-Cell Level

CD8(+) T cells are important effectors of adaptive immunity against pathogens, tumors, and self antigens. Here, we asked how human cognate antigen-responsive CD8(+) T cells and their receptors could be identified in unselected single-cell gene expression data. Single-cell RNA sequencing and qPCR of...

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Detalles Bibliográficos
Autores principales:	Fuchs, Yannick F., Sharma, Virag, Eugster, Anne, Kraus, Gloria, Morgenstern, Robert, Dahl, Andreas, Reinhardt, Susanne, Petzold, Andreas, Lindner, Annett, Löbel, Doreen, Bonifacio, Ezio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851025/ https://www.ncbi.nlm.nih.gov/pubmed/31781096 http://dx.doi.org/10.3389/fimmu.2019.02568

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