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Monocytes reprogrammed with lentiviral vectors co-expressing GM-CSF, IFN-α2 and antigens for personalized immune therapy of acute leukemia pre- or post-stem cell transplantation

Acute myeloid leukemia (AML) is the most common acute leukemia in adults and overall survival remains poor. Chemotherapy is the standard of care for intensive induction therapy. Patients who achieve a complete remission require post-remission therapies to prevent relapse. There is no standard of car...

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Detalles Bibliográficos
Autores principales: Bialek-Waldmann, Julia K., Heuser, Michael, Ganser, Arnold, Stripecke, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851032/
https://www.ncbi.nlm.nih.gov/pubmed/31628525
http://dx.doi.org/10.1007/s00262-019-02406-9

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